Hepatitis E virus genotype 1 (isolate Human/China/HeBei/1987) (HEV)

Taxonomy: Viruses; ssRNA viruses; ssRNA positive-strand viruses, no DNA stage; Hepeviridae; Hepevirus; Hepatitis E virus

Average proteome isoelectric point is 7.64

Get precalculated fractions of proteins

Acidic
pI < 6.8
6.8-7.4
pI > 7.4
Basic
    
All


Virtual 2D-PAGE plot for 3 proteins (isoelectric point calculated using IPC_method)

Get csv file with sequences according given criteria:
        -     Method 

     -  kDa    
                                                                                      

* You can choose from 18 different methods for calculating isoelectric point
Protein with the lowest isoelectric point:
>sp|Q81862|POLN_HEVCH Non-structural polyprotein pORF1
MEAHQFIKAPGITTAIEQAALAAANSALANAVVVRPFLSHQQIEILINLMQPRQLVFRPEVFWNHPIQRVIHNELELYCRARSGRCLEIGAHPRSINDNPNVVHRCFLRPAGRDVQRWYTAPTRGPAANCRRSALRGLPAADRTYCFDGFSGCNFPAETGVALYSLHDMSPSDVAEAMFRHGMTRLYAAL
HLPPEVLLPPGTYRTASYLLIHDGRRVVVTYEGDTSAGYNHDVSNLRSWIRTTKVTGDHPLVIERVRAIGCHFVLLLTAAPEPSPTPYVPYPRSTEVYVRSIFGPGGTPSLFPTSCSTKSTFHAVPAHIWDRLMLFGATLDDQAFCCSRLMTYLRGISYKVTVGTLVANEGWNASEVALTAVITAAYLTI
CHQRYLRTQAISKGMRRLEREHAQKFITRLYSWLFEKSGRDYIPGRQLEFYAQCRRWLSAGFHLDPRVLVFDESAPCHCRTAIRKAVSKFCCFMKWLGQECTCFLQPAEGAVGDQGHDNEAYEGSDVDPAESAISDISGSYVVPGTALQPLYQALDLPAEIVARAGRLTATVKVSQVDGRIDCETLLGNK
TFRTSFVDGAVLETNGPERHNLSFDASQSTMAAGPFSLTYAASAAGLEVRYVAAGLDHRAVFAPGVSPRSAPGEVTAFCSALYRFNREAQRLSLTGNFWFHPEGLLGPFAPFSPGHVWESANPFCGESTLYTRTWSEVDAVSSPAQPDLGFISEPSIPSRAATLTPAAPLPPPAPDPSPTPSAPARGEPA
PGATARAPAITHQAARHRRLLFTYPDGSKVFAGSLFESTCTWLVNASNVDHRPGGGLCHAFYQRYPASFDAASFVMRDGAAAYTLTPRPIIHAVAPDYRLEHNPKMLEAAYRETCSRLGTAAYPLLGTGIYQVPIGPSFDAWERNHRPGDELYLPELAARWFEANRPTCPTLTITEDVARTANLAIELDS
ATDVGRACAGCRVTPGVVQYQFTAGVPGSGKSRSITQADVDVVVVPTRELRNAWRRRGFAAFTPHTAARVTQGRRVVIDEAPSLPPHLLLLHMQRAATVHLLGDPNQIPAIDFEHAGLVPAIRPDLAPTSWWHVTHRCPADVCELIRGAYPMIQTTSRVLRSLFWGEPAVGQKLVFTQAAKAANPGSVTV
HEAQGATYTETTIIATADARGLIQSSRAHAIVALTRHTEKCVIIDAPGLLREVGISDAIVNNFFLAGGEIGHQRPSVIPRGNPDANVDTLAAFPPSCQISAFHQLAEELGHRPAPVAAVLPPCPELEQGLLYLPQELTTCDSVVTFELTDIVHCRMAAPSQRKAVLSTLVGHYGRRTKLYNASHSDVRDS
LARFIPAIGHVQVTTCELYELVEAMVEKGQDGSAVLELDLCNRDVSRITFFQKDCNKFTTGETIAHGKVGQGISAWSKTFCALFGPWFRAIEKAILALLPQGVFYGDAFDDTVFSAAVAAARASMVFENDFSEFDSTQNNFSLGLECAIMVECGMPQWLIRLYHLIRSAWILQAPKESLRGFWKKHSGEP
GTLLWNTVWNMAVITHCYDFRDLQVAAFKGDDSIVLCSEYRQSPGAAVLIAGCGLKLKVDFRPIGLYAGVVVAPGLGALPDVVRFAGRLTEKNWGPGPERAKQLRLAVSDFLRKLTNVAQMCVDVVSRVYGVSPGLVHNLIGMLQAVADGKAHFTESVKPVLDLTNSILCRVE
Molecular weight: 185.05 kDa
Isoelectric point according different methods:





Protein with the highest isoelectric point:
>sp|Q81871|CAPSD_HEVCH Capsid protein
MRPRPILLLLLMFLPMLPAPPPGQPSGRRRGRRSGGSGGGFWGDRADSQPFAIPYIHPTNPFAPDVTAAAGAGPRVRQPARPLGSAWRDQAQRPAAASRRRPTTAGAAPLTAVAPAHDTPPVPDVDSRGAILRRQYNLSTSPLTSSVATGTNLVLYAAPLSPLLPLQDGTNTHIMATEASNYAQYRVVRA
TIRYRPLVPNAVGGYAISISFWPQTTTTPTSVDMNSITSTDVRILVQPGIASEHVIPSERLHYRNQGWRSVETSGVAEEEATSGLVMLCIHGSLVNSYTNTPYTGALGLLDFALELEFRNLTPGNTNTRVSRYSSTARHRLRRGADGTAELTTTAATRFMKDLYFTSTNGVGEIGRGIALTLFNLADTLL
GGLPTELISSAGGQLFYSRPVVSANGEPTVKLYTSVENAQQDKGIAIPHDIDLGESRVVIQDYDNQHEQDRPTPSPAPSRPFSVLRANDVLWLSLTAAEYDQSTYGSSTGPVYVSDSVTLVNVATGAQAVARSLDWTKVTLDGRPLSTTQQYSKTFFVLPLRGKLSFWEAGTTKAGYPYNYNTTASDQLL
VENAAGHRVAISTYTTSLGAGPVSISAVAVLAPHSALALLEDTMDYPARAHTFDDFCPECRPLGLQGCAFQSTVAELQRLKMKVGKTREL
Molecular weight: 70.98 kDa
Isoelectric point according different methods:





General Statistics

Number of major isoforms

Number of additional isoforms

Number of all proteins

Number of amino acids

Min. Seq. Length

Max. Seq. Length

Avg. Seq. Length

Avg. Mol. Weight

3

0

3

2,467

114

1,693

822.3

89.2 kDa
Amino acid frequency

Ala

Cys

Asp

Glu

Phe

Gly

His

Ile

Lys

Leu

Met

Asn

Gln

Pro

Arg

Ser

Thr

Val

Trp

Tyr

11.31

2.31

4.38

4.3

3.97

7.3

2.8

3.93

1.91

9.4

1.34

2.84

3.4

7.86

7.22

6.97

7.13

7.38

1.34

2.92
Note: For statistics only major isoforms were used (in this case 3 proteins)
For dipeptide frequency statistics click here
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI: proteome isoelectric point database. Nucleic Acids Res. 2016. doi: 10.1093/nar/gkw978       Contact: Lukasz P. Kozlowski